Found 33 matching trials
Study of AMG 509 in Participants With Metastatic Castration-Resistant Prostate Cancer PHASE1 The overall aim of the trial is to evaluate the safety, tolerability, and p...
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City of Hope National Medical Center
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Using Genetic Profile to Determine the Treatment for Patients With Ovarian Cancer Who Previously Received a PARP-inhibitor PHASE2 The purpose of this research study is to see how useful it is to look at bi...
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Princess Margaret Cancer Centre
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Niraparib Efficacy in Patient With Unresectable Mesothelioma PHASE2 Multicentre, 2 arm, open-label UK randomised phase II trial to determine th...
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University Hospital Southampton, Southampton General Hospital
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REVITALIZE: RCT to Reduce Fatigue in Adults With Ovarian Cancer on PARP Inhibitors NA The purpose of this study is to see whether a supportive intervention (REVI...
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University of Colorado Cancer Center-Anschutz
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Pembrolizumab With Olaparib as Combined Therapy in Metastatic Pancreatic Cancer PHASE2 A phase II study combining pembrolizumab with olaparib in metastatic pancre...
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SMMART Adaptive Clinical Treatment (ACT) Trial EARLY_PHASE1 SMMART-ACT is a feasibility pilot study to determine if testing samples fro...
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Multiple Locations
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A Study to Investigate Biomarker Effects of Pre-Surgical Treatment With DNA Damage Repair (DDR) Agents in Patients With Head and Neck Squamous Cell Carcinoma (HNSCC). PHASE1 This biomarker study has been designed to assess the effects of different a...
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Response to PARP Inhibitor Predicted by the RAD51 Assay PHASE2 In tumors with a defect in the homologous recombination (HR) pathway, doubl...
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Multiple Locations
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Targeted Agent Evaluation in Digestive Cancers in China Based on Molecular Characteristics NA This a prospective real-world navigation study using tumor DNA sequencing t...
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Active Not Recruiting
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Peking University Cancer Hospital
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A Single-Arm Phase Ⅱ Study of Fluzoparib Maintenance in Platinum-sensitive Advanced Triple-Negative Breast Cance PHASE2 Breast cancer is the most common malignancy in women; approximately 5-10% a...
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Tianjin Medical University Cancer Institute and Hospital
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